Depression linked to obesity due to dietary fats entering the brain
Leisure Opportunities
Job search
Job Search
see all jobs
Latest job opportunities
star job
Chatsworth House
Competitive
Bakewell, UK
Nutfield Priory Hotel and Spa
Competitive salary plus benefits
Nutfield Priory Hotel & Spa
Aspria
Competitive
Italy
Circadian Leisure Trust
£19,644.04
Bristol, UK
Legoland Discovery Centre
Competitive
Tempe, Arizona, USA

Depression linked to obesity due to dietary fats entering the brain

Job opportunities
Fit This
Competitive + uncapped commission (OTE £28K)
location: Hackney, London, UK
training opportunity
Focus Training
location: Nationwide, United Kingdom
EMD UK
Competitive
location: Horsham, UK
more jobs
This research may begin to explain how and why obesity is linked with depression
– George Baillie

Researchers have linked the consumption of diets high in saturated fats – which lead to obesity – with the development of depression phenotypes.

A study led by the University of Glasgow, in collaboration with the Gladstone Institutes, showed that saturated fatty acids enter into the brain's hypothalamus region, which is related to the metabolic system and is known to be linked to depression.

Published in the journal Translational Psychiatry, the research also showed that fatty acids affected key signalling pathways that are known to be responsible for the development of depression.

Another finding was that by decreasing the expression of a specific enzyme called phosphodiesterase, symptoms of obesity-linked depression could be reduced.

It is hoped that the study will finally shed some light on the links between obesity and depression. Previous clinical studies have found a strong association between the two conditions, but – until now – the exact mechanisms of how obesity affects depression and vice versa have not been fully understood.

“This is the first time anyone has observed the direct effects a high fat diet can have on the signaling areas of the brain related to depression," said professor George Baillie, lead author of the study.

"This research may begin to explain how and why obesity is linked with depression and how we can potentially better treat patients with these conditions.

“We all know that a reduction in fatty food intake can lead to many health benefits, but our research suggests that it also promotes a happier disposition.

"Further to that, understanding the types of fats, such as palmitic acid, which are likely to enter the brain and affect key regions and signaling will give people more information about how their diet can potentially affect their mental health.”

For the study – using mice – researchers studies were able to see that saturated fatty acids were actually entering the brain via the bloodstream and thereafter accumulate and affect crucial brain signals related to depression.

Mice fed a fat-dense diet (made up of 60 per cent saturated and unsaturated fats) were shown to have an influx of dietary fatty acids in the hypothalamus region of the brain, an area related to the metabolic system and known to be linked with depression.

These fatty acids were then able to directly affect the key signaling pathways responsible for the development of depression.

To read the full study, click here for Translational Psychiatry

• To read an article discussing whether exercise prescription could help tackle depression, click here for HCM magazine Issue 5 2018.

Sign up for FREE ezines & magazines
Researchers have linked the consumption of diets high in saturated fats – which lead to obesity – with the development of depression phenotypes.
HAF,FIT,IND,PTS,ACD,RES,PUB
imagesX/THUMB341807_223706_428283.jpg

More News

1 - 15 of 38,714
22 May 2019
Balance training is increasing in popularity among fitness operators and users. The emergence of balance training as a growing trend was identified by HCM in ... More
22 May 2019
Attendance at the world's major waterparks continues to grow, with nearly 31 million people visiting the top waterparks globally in 2018. According to the latest ... More
22 May 2019
2018 was a landmark year for the themed entertainment industry, with the latest edition of the TEA/AECOM Theme and Museum Index showing the world's major ... More
22 May 2019
There will be more guaranteed play at this year's Wimbledon Tennis Championships – thanks to the completion of a three-year project to cover the famous ... More
21 May 2019
High-end boxing gym brand BXR is looking to roll out an expansion of its Sweat by BXR group exercise concept in the UK, with founder ... More
21 May 2019
Sports psychologist Jeremy Snape and Olympic gold medallist Amy Williams are among the keynote speakers at this year's Active Uprising. Snape will draw on insights ... More
STA
STA
21 May 2019
The Co-operative Group (Co-op) will invest a "multi-million-pound" sum to help create a network of street gyms in areas impacted by knife crime. Working in ... More
21 May 2019
There is nothing new in facility operators reconfiguring underused sports courts as gyms and exercise studios in order to cater to changing demands. Monmouthshire County ... More
20 May 2019
A new collaboration between Sport England, think tank Demos and care and housing provider Anchor Hanover looks to get the over 55s in the UK ... More
20 May 2019
UK-based The Massage Company (TMC) has signed a deal with FranGlobal, Asia’s largest franchise reseller, to open 50 massage centres across India, potentially delivering up ... More
20 May 2019
Exercise has been shown to have a positive impact on people's mental health, but is the health club sector doing the most it can, both ... More
20 May 2019
Scottish Secretary David Mundell has met with Lawn Tennis Association (LTA) chief executive Scott Lloyd to discuss plans to develop the sport in Scotland and ... More
Focus Training
Focus Training
20 May 2019
A survey of UK gym users has found that a third (34 per cent) of gym users said they were aware of other members at ... More
17 May 2019
Inspired to encourage children to develop a lasting relationship with plants and nature, Royal Botanic Gardens, Kew in London is all set to open its ... More
17 May 2019
The UK health and fitness industry is healthier than it has ever been, according to The 2019 State of the UK Fitness Industry Report. Published ... More
ukactive
ukactive
1 - 15 of 38,714
STA-Swimming Teachers Association
STA-Swimming Teachers Association