 |
COVID-19 attacks fat cells – could explain why people with obesity are at higher risk
13 Dec 2021
New research suggests that COVID-19 infects fat cells, explaining why overweight and obese are at a higher risk of severe illness and death from COVID-19.
The study, led by Stanford University School of Medicine, examined whether fat tissue obtained from bariatric surgery patients could become infected with the virus, and tracked how various types of cells responded to the virus.
It found that fat cells and also immune cells (macrophages) can be infected, leading to a 'robust inflammatory response'.
The findings show the virus is able to evade the immune defences within the body's fat cells, before causing inflammation elsewhere in the body and could help explain why patients with excess body weight are particularly vulnerable to the virus – and also why some younger adults with no underlying health issues become so ill.
The research will reinforce the importance of work being done in the health and fitness and spa and wellness industries, to help people control and reduce their percentage body fat.
Liz Terry, editor of HCM magazine and editorial director of Spa Business magazine, said: "The health and fitness and spa and wellness sectors have been lobbying governments around the world to gain essential service status, so our health clubs and spa and wellness businesses can always be there to support people with their health as we grapple with the pandemic.
"Research such as this, from such an eminent source, lends weight to this argument and as we discover more about the SARS-Cov-2 virus and its many mutations, it becomes clear that our industries have a vital role to play in supporting individuals and governments to battle this challenge.
"Our sectors must continue to present evidence, such as this in, support of our bids to be recognised as essential."
THE DETAIL
In reporting the details of the findings, the researchers said: "Collectively, our findings indicate that adipose (fat) tissue supports SARS-CoV-2 infection and pathogenic inflammation and may explain the link between obesity and severe COVID-19.
"Obesity is associated with adverse COVID-19 outcomes, but the underlying mechanism was unknown.
"We demonstrate that human fat tissue is 'permissive' to SARS-CoV-2 infection – the virus that causes COVID-19 – and that infection elicits an inflammatory response, including the secretion of known inflammatory mediators of severe COVID-19.
"We identify two cellular targets of SARS-CoV-2 infection in adipose tissue: mature adipocytes and adipose tissue macrophages.
"Adipose tissue macrophage infection is largely restricted to a highly inflammatory subpopulation of macrophages, present at baseline, that is further activated in response to SARS-CoV-2 infection.
"Preadipocytes, while not infected, adopt a pro-inflammatory phenotype. We further demonstrate that SARS-CoV-2 RNA is detectable in adipocytes in COVID-19 autopsy cases and is associated with an inflammatory infiltrate.
The research has not yet been peer-reviewed, but has been published online.
back
|
| Latest member news |
 |
|
Community Leisure UK’s Active Kindness project celebrates after being awarded £651,003 in National Lottery funding
Active Kindness, a volunteering programme which previously received Sport England
funding, is celebrating after receiving vital National Lottery funding to leverage
the power of volunteering across public leisure and culture to create greater
community cohesion, stronger personal development of individuals and increase the
diversity of those taking part in health, wellbeing, and creative programmes.
read more...
Edinburgh Leisure Appoints New Chief Executive
Edinburgh-based physical activity charity, Edinburgh Leisure, has announced the
appointment of a new Chief Executive.
read more...
Withington Baths Receives Sports England Grant to Accelerate its Carbon Footprint Reduction Efforts
Love Withington Baths, the non-profit organisation that operates Withington Baths
and co-working space Withington Works, has announced exciting plans to
significantly reduce its carbon footprint and enhance energy efficiency thanks to
a £105K grant secured from Sport England under the Government’s Swimming Pool
Support Fund.
read more...
GLL Celebrate £140k Arts Council Funding
VR headsets, IT hublets and improved seating, shelving and flooring are on their
way to Lye Library, Dudley thanks to funding from the Arts Council.
read more...
Much-Loved Library to Receive Grant Funding of Nearly £400,000
One of Redbridge's most popular libraries will benefit from a significant
modernisation programme after being awarded nearly £400,000 in grant funding.
read more...
Horizon Leisure Scoops Prize at Portsmouth Business Awards
Horizon Leisure, which operates Havant leisure Centre and Waterlooville Leisure
Centre, was crowned Community Business of the Year at the Portsmouth Business
Awards earlier this year.
read more...
Portsmouth Tennis Centre celebrated for bringing tennis to all
Portsmouth Tennis Centre has been recognised by the LTA Tennis Awards for bringing
tennis to under-represented groups and communities throughout the city.
read more...
|
|
Wellness Hub Breaks Down Barriers to Tackle Health Inequalities in North East Lincolnshire
A new report on Lincs Inspire’s Wellness Hub has revealed the difference it is
making to community health.
read more...
Grant from Parkinson’s UK Gives Green Light to New Cycle Classes
Everybody Health & Leisure has launched a dedicated group cycling classes for
people living with Parkinson's Disease.
read more...
Doncaster Culture and Leisure Trust score partnership with Club Doncaster
Doncaster Culture and Leisure Trust (DCLT) and Club Doncaster have agreed a
partnership that will see DCLT as an official sponsor of the Dons RLFC and sponsor
of two Belles players.
read more...
BPL Achieves Swim England’s Water Wellbeing Accreditation
AWARD winning community leisure trust BPL has achieved Swim England’s Water
Wellbeing accreditation.
read more...
Edinburgh Leisure Scale New Heights Following £100,000 Boost
Edinburgh Leisure’s flagship climbing arena at Ratho has benefitted from a major
funding investment from sportscotland’s Sport Facilities Fund.
read more...
78-year-old George’s marvellous weightlifting medicine
Almost an octogenarian, George Travis is still hammering out kettle bell classes
as an Active Tameside fitness instructor.
read more...
Cefn Hengoed Leisure Centre Gets Massive Makeover
A Swansea leisure centre has been totally revamped with a £7.5 million investment.
read more...
|
| Business partner news |
|
|
|
|
09 Apr 2024
Oxygen Consulting deep dives into padel with forthcoming report
Oxygen Consulting is about to launch its first UK Padel Report, which
investigates this fast-growing sport.
read more...
05 Apr 2024
Ronaldo crashes the app store with launch of new wellness, fitness and health app, Erakulis
Portugese footballer, Cristiano Ronaldo, has launched a health and wellness app that harmonises
advice on fitness, nutrition and mental wellness in one seamless experience.
read more...
04 Apr 2024
New research shows BMI fails as a measure of childhood obesity, leading to flawed policy
Waist circumference-to-height ratio is a more reliable measure of obesity in children and
adolescents than BMI according to a new study, published in Pediatric Research.
read more...
28 Mar 2024
4Global and UK Active launch private sector health club benchmarking
The first annual Private Sector Benchmarking report was released today (27 March). A
collaboration between UK Active and 4Global, the aim of the research is to provide accurate
insight into the state of UK-based private sector health clubs.
read more...
|
|
27 Mar 2024
Egym snaps up Hussle as it moves to dominate the corporate wellness market with its Wellpass product
Egym, has signalled its intention to become a dominant force in the corporate wellness sector
with the acquisition of UK-based aggregator, Hussle.
read more...
26 Mar 2024
Total Fitness turns a profit as it beats pre-COVID membership
Total Fitness has released results for its most recent financial year (to June 23), which saw a
return to pre-COVID membership levels following a year-on-year uplift in membership numbers
of 5 per cent.
read more...
25 Mar 2024
Entrepreneurs share secrets of building a fitness business at PerformX
Enjoy building your business because the journey can be as good or better than the destination
was one takeaway of the industry titans’ panel on empire building, comprised of three industry
entrepreneurs.
read more...
22 Mar 2024
Myzone removes the hardware barrier with launch of MZ-Open, making its system available on smart watches
Myzone is now available on smart watches, allowing Android and AppleWatch wearers to record
workouts without an additional device, and taking the tech company into the multi-billion dollar
smart watch market.
read more...
|
|
|
|
| General Meetings |
 |
|
CLUK General Meeting
15 May 2024: Glasgow
|
| Special Interest Groups |
|
|
Social Value
16 April 2024
|
Volunteering
24 April 2024
|
Finance
2 May 2024
|
|
For more information about Special Interest Group and regional / national members meetings, please contact [email protected]
|
| Job vacancies |
|
|
Team Leader (Harrow School Fitness Club)
Salary: £13.71 per hour
Location: Harrow on the Hill, Harrow, UK
Company: Harrow School
Read more and apply
|
Centre Manager (Leisure)
Salary: £40,221 - £42,403pa + pension + benefits
Location: Exeter, UK
Company: Exeter City Council
Read more and apply
|
Director of Operations
Salary: £61,000 - £64,000 + exceptional pension + excellent benefits
Location: Luton, UK
Company: Active Luton
Read more and apply
|
Membership Manager
Salary: £29,605 - £32,982pa + pension + benefits
Location: Coventry, UK
Company: University of Warwick
Read more and apply
|
Chief Executive Officer, Mount Batten Centre
Salary: c£65,000pa + pension + benefits
Location: Plymouth, UK
Company: Mount Batten Group
Read more and apply
|
|
